Epidemiology and Etiology of Renal calculi

Image Drug Designing: Open Access, is an peer-reviewed, open-access scholarly journal focused on publishing articles in all aspects of academic journal and aims to publish most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers w... Read More

Antioxidant Activity of Polyphenolic Flavonoid of herbals

Image   Objective: Phytochemical constituents of herbal extracts has shown positive response of antioxidant activity. The purpose of the present study was to investigate the antioxidant activity of polyphenolic flavonoids in the ethanolic extract of stem of Nicotiana tabacum. Materials and Methods: Flavonoids contents were determined by both thin layer chromatography and aluminium chloride colorimetric method, where as phenolic content was determine by Folin-Ciocalteau method. Antioxidant activity was observed by determin... Read More

Lentinan Exerts its Anti-Inflammatory Activity by Suppressing TNFR1 Transfer to the Surface of Intestinal Epithelial Cells through Dectin-1 in an in vitro and mice model

Image Lentinan Exerts its Anti-Inflammatory Activity by Suppressing TNFR1 Transfer to the Surface of Intestinal Epithelial Cells through Dectin-1 in an in vitro and mice model It has been reported that lentinan, β-1,3; 1,6-glucan derived from Lentinula edodes, suppresses intestinal inflammation and ameliorates symptoms of colitis. However, the mechanism of intestinal anti-inflammatory activity of lentinan and how it is recognized by intestinal epithelial cells remains largely unclear. The receptor for lentinan on intestinal epithelial cells was identified using an ... Read More

Computer Aided Drug Designing

Image Drug Designing: Open Access is an scientific, peer reviewed journal that covers research original articles, review articles, case reports, short communications, etc. in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers worldwide. Computational approaches are useful tools to interpret and guide experiments to expedite the antibiotic drug design process. Structure based ... Read More

Developing Electronic-nose Technologies for Clinical Practice

Image Developing Electronic-nose Technologies for Clinical Practice The development of relatively simple gas-sensing devices with sensor arrays capable of constructing molecular profiles of complex Volatile Organic Compound (VOC) metabolites from clinical samples, based on production of healthy or disease-specific digital signature patterns, may soon help to revolutionize diagnostic procedures in clinical practice. This mini-review summarizes the development of recent portable electronic-nose (e-nose) technologies as new diagnostic tools with the potential for accelerat... Read More

Modern Approaches in Drug Designing & Drug Designing

Image Drug Designing: Open Access is a peer-reviewed multidisciplinary scholarly journal aims to publish reliable source of scientific information on Drug Research and applied fields. The Journal aims to provide platform for the researchers, expertise in physics sciences disciplines, for disseminating experimental and theoretical reports reporting the progress of Physics Research and its advancing significant interdisciplinary applications  Latest research in all related fields o... Read More

Drug Designing

Image  Drug Designing: Open Access   Gives dependable data upgrade to online viewers with the adapted methods and most advancement in the field on designing new drugs, research and developments, clinical experiments, drug delivery systems, and adverse events, biochemistry and pharmacological aspects. The idiosyncratic reactions are unpredictable from the pharmacological action of the drug. Genes are also associated with ADRs; genes that consistently exhibit increa... Read More

Drug: Discovery Research

Image The Journal Drug Designing: Open Access aims to fill this important knowledge barrier for decades. Here the Journal tries to provide a platform for them to meet their existence with the commitment to the research society by publishing their latest research. The Journal has been dealing with the case reports, original research and review articles about the pharmaceutical intervention safety, side effects, and adverse effects as well as medication toxicity. Drug Discover... Read More

Commentary on “Gallbladder Cancer: South American Experience

Image Commentary on “Gallbladder Cancer: South American Experience When I was invited by Dr. Ghassan Abou-Alfa to write an article about the South American experience in gallbladder cancer (GC) I felt enthusiasm. It was an opportunity to make a contribution to this public health problem. GC is among the leading causes of death from cancer in women in many Western areas in my country Argentina and in South America.  Based on their daily practice experience many health workers in Salta, the province where I live at the northwest of Argentina, know that GC is a loc... Read More

MicroRNAs in Skin Biology: Biogenesis, Regulations and Functions in Homeostasis and Diseases

Image MicroRNAs in Skin Biology: Biogenesis, Regulations and Functions in Homeostasis and Diseases The progression in science gives novel and deeper understandings of human beings organisms. The Human Genome Project uncovered about 20,500 human genes. More recently, non-coding RNAs saw the light and gained researchers interest. Among the different subsets of these non-coding RNAs, microRNAs were identified as 18-25 nucleotides long and have been shown to play critical regulatory roles in a wide range of cellular processes. Emerging studies highlighted the importance of ... Read More

Parathyroid Carcinoma has a PD-L1 Expression, and Share with Atypical Neoplasms an Abundant Intratumoral Macrophagic

Image Parathyroid Carcinoma has a PD-L1 Expression, and Share with Atypical Neoplasms an Abundant Intratumoral Macrophagic Aim: The aim of this study was characterized programmed death-ligand 1 (PD-L1) expression and tumoralinfiltrating lymphocytes (TILs) in parathyroid carcinoma (PC) and atypical parathyroid neoplasms (ANs). Methods: Our tissue samples constitute 30 parathyroid tumors (17 PC and 13 ANs) which were available from a prospectively collected database at the University of Texas M.D Anderson Cancer Center from 1... Read More

Computer-aided design of inhibitors of DNA methyl transferases

Image The team “Drug Designing: Open Access”, welcomes you to the most accessed “open access publication – Longdom Publishing” page with 25+ Million reader base. The Journal of Drug Designing: Open Access progresses forward reviewing and disseminating the recent advances in pharmaceutical industry with focus towards the drug discovery, drug design by rational approach. Longdom Publishing hosts around 215 open access ... Read More

Specificity of Heparin/Heparan sulphate binding to proteins

Image The Journal, Drug Designing: Open Access publishes the highest quality scientific articles amalgamating broad range of fields including molecular modeling, clinical research and drug discovery and delivery. Heparin/heparan sulphate? Protein interactions modulate a number of physiological processes such as coagulation, immune response, angiogenesis, and morphogenesis and pathogen infection. A majority of these interactions involve allosteric regulation of the target protein and a... Read More

Explore Novel Ideas in Developing Drugs

Image Journal of Developing Drugs is a peer-reviewed Journal, encourages on-going international research and information exchange through publication of latest advances.   The Journal is pleased to inform that it is been running successfully since 8 years and is running towards its 9th Anniversary. It is an Open access scholarly Developing Drugs journal with an ISSN No: 2329-6631. This journal is known for its quality research articles in the field of Pharmaceutics, Nanotechnology, Novel Drug Delivery Systems, Quality Control, Quality Assurance, International Regulatory, ... Read More

Journal of Antivirals & Antiretrovirals Manuscript Submission

Image Journal of Antivirals & Antiretrovirals - Open Access using online manuscript submission, review and tracking systems of Longdom Publishing for quality and quick review processing. Longdom Publishing is using Online Review and Editorial Manager Systems for quality review process. Editorial Manager System is an online submission and review system, where authors can submit manuscripts and track their progress. Reviewers can download manuscripts and submit their opinions. Editors can manage the whole submission/review/revise/publish process. Publishers can see what manuscripts ar... Read More

Drug Designing: Open Access | Manuscript Submission

Image Journal of Drug Designing: Open Access is using online manuscript submission, review and tracking systems of Longdom Publishing SL for quality and quick review processing. Longdom Publishing SL is using Online Review and Editorial Tracking Systems for quality review process. Editorial Managerial System is an online submission and review system, where authors can submit manuscripts and track their progress. Reviewers can download manuscripts and submit their opin... Read More

Conference Announcement & Article Submission on Drug Discovery 2020

Image Co The perspective of the Drug Discovery Conference is to set up novel research techniques to help researchers understand how innovative techniques have advanced and how the field has developed in recent years. The pharmaceutical industry channels an important proportion of total research in most developed countries. In Europe, for example, it represents about 13% of total R&D. In recent years, pharmaceutical companies have been... Read More

Scientific Survey on Drugs and its Metabolites

Image Journal of Developing Drugs is an open access Scientific Journal which mainly focuses on articles of Drug designing. The Journal of Developing Drugs comes up with an opportunity to researchers and scientist to explore advance research in Drug Development. The Journal of Developing Drugs is of highest standards in terms of quality.   The editorial team of Developing Drugs and Research is overwhelmed by the response and eagerness of the academic and research contr... Read More

Scope of Drug Designing: Open Access Journal

Image   Scope of Drug Designing: Open Access Journal   Drug Designing: Open Access is an international peer reviewed open access journal presenting original research and contributions and scientific advances in the field of drug design and development. Drug Designing  journal welcomes research articles, review articles, letter to the editors, editorials, case reports and innovations relating to all aspects of drug design and dev... Read More

Statistical Designs for Pharmaceutical

Image Statistical Designs for Pharmaceutical Drug Designing: Open Access is a scientific open access journal that specifies and describes the development activities conducted in the fields of including molecular modeling, clinical research and drug discovery and delivery. In recent years, the concept of quality by design in (global) pharmaceutical development has received much attention. The purpose is to ensure that the compound under investigation wil... Read More

Risk Factors for Febrile Seizures in Children

Image Risk Factors for Febrile Seizures in Children Objective: we aimed to identify the factors associated with febrile seizures (FS) occurrence. Methods: This was a case-control study. Sixty cases of FS were prospectively recorded and compared to 60 controls admitted for fever without seizures.   Baseline Data were collected from all consecutive patients and laboratory hematological parameters including complete blood count, serum iron, serum ferritin and zinc levels were perform... Read More

The Presence of Autonomous and Non-Autonomous Replication in Cancer and their Connection through Inflammation

Image The Presence of Autonomous and Non-Autonomous Replication in Cancer and their Connection through Inflammation Targeted therapy with small molecule such as TKI (tyrosine kinase inhibitor) against EGFR has achieved high response rate and significant clinical benefits in selected group of lung cancer patients in the past decade. One reliable criterion for patient selection is the presence of certain mutations in the EGFR gene such as mutations in exon-19, 20 or 21 in lung cancer patients. In these patients, it is often observed that TKI therapy could be so effective ... Read More

Special Issue on Drug Designing : Edited by Guest Editors

Image Special Issue on Drug Designing : Edited by Guest Editors The Drug Designing: Open Access is a peer-reviewed, open-access scholarly journal .journal have been showing tremendous citations and articles focusing the most advanced research trends in the field of drug discovery, medicinal chemistry, Drug Design tools, protein engineering, bioinformatics. As a Managing Editor it is my great pleasure to invite Guest editors and Eminent Authors to participate in ... Read More

Pemphigus Herpetiformis with Only Positive Anti-Envoplakin Antibodies

Image Pemphigus Herpetiformis with Only Positive Anti-Envoplakin Antibodies Pemphigus herpetiformis, first described in 1975, is a rare subtype of autoimmune bullous disease that associates clinical features of dermatitis herpetiformis with immunological features of pemphigus. We present a 48-years-old female patient, with pruritic lesions located mainly in the upper limbs with 6 years of evolution. Physical examination revealed erythematous papules, some excoriated and vesicles of translucent content distributed on her arms, trunk and neck. Histological examination of ... Read More

Autoimmune Hemolytic Anemia and Thrombocytopenia with Tuberculous Lymphadenitis

Image Autoimmune Hemolytic Anemia and Thrombocytopenia with Tuberculous Lymphadenitis  Well-differentiated small-intestinal neuroendocrine tumors (SI-NETs) tend to be biologically indolent.Despite this tendency, they have a predilection for metastasis. Peritoneal involvement is quite common as isunfortunately peritoneal carcinomatosis (PC). PC is a dreaded metastatic complication due to the significant morbidity it creates for patients as well as well as increasing their mortality risk. The risk factors for PC development in SI-NETs remain understudied; however, on... Read More

Journal of Drug Designing: Open Access | Celebrating 9th Anniversary

Image Journal of Drug Designing: Open Access | Celebrating 9th Anniversary Journal of Drug Designing: Open Access is about to complete its 8 years of publication in the field of Science and Technology. During the span of 8 years it has provided a large platform for scientists, scholars, researchers with ease in the publication process and gained lot of reputation among the scientific community which helps the journal to emerge as one the biggest journ... Read More

An insight to Biology and Medicine

Image Journal of Biology and Todays World is a perfect Insight for the readers related to Biology and Medicine. It has a vast scope and is currently running since 8 years with many successful quality articles published. Due its broad scope, a diverse set of topics, such as genetics, biotechnology, biochemistry, microbiology, cellular & molecular biology, and disease biology, are covered under the aegis of this journal. Additionally, the journal also provides rapid, authoritative, and insightful reports and interpretation of topical and future trends in science. ... Read More

Reviewing the progression in Drug Designing research

Image Reviewing the progression in Drug Designing research The team “Drug Designing: Open Access”, welcomes you to the most accessed “open access publication – Longdom Publishing” page with 25+ Million reader base. The Journal of Drug Designing: Open Access progresses forward reviewing and disseminating the recent advances in pharmaceutical industry with focus towards the drug discover... Read More

Pathology: A big innovation to medicine

Image Pathology: A big innovation to medicine   Journal of Medical and Surgical Pathology (JMSP) has announced almost 20 percent discount on article processing charge to commemorate its 4th Anniversary. The Editorial Board of Journal of Medical and Surgical Pathology is overwhelmed by the response and eagerness of the academic and research contributors to publish with the journal and take part in the 4th anniversary celebrations. During this year we look forward to taking some initiatives that would encourage and rewar... Read More

Emerging Trends in Developing Drugs

Image On behalf of the Journal of Developing Drugs, as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been ten long years we have started the Journal, now we are celebrating the 10th Anniversary and we are privileged to welcome Innovative Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome you to the Journal of Developing Drugs. The Journal of Developing Drugs aims to disseminate knowledge and pr... Read More

Second-line Anti-Tuberculosis Drugs and Risk of Alopecia: A Retrospective Cohort study

Image Alopecia is not a well-known adverse effect of second-line anti-tuberculosis drugs. It is, however, been frequently reported in Eritrea and 83% of the reports of alopecia associated with second-line anti-TB drugs in the global adverse drug reaction database, as of July 25, 2017, were submitted from Eritrea. It is wondering why this much variation is happening and this study is therefore aimed at quantifying the risk, identifying possible risk factors and elucidating the causal association between alopecia and the second-line anti-TB drugs in Eritrea. This was an observational cohort study o... Read More

Malaria research advances immunotherapy in lupus, HIV

Image On behalf of the Immunotherapy: Open Access, as Editor-in-Chief, it is my distinct honour and privilege to inform you that, it’s been four long years we have started the Journal, now we are celebrating the 4th Anniversary and we are privileged to welcome immunological Society to our journal. As Editor-In-Chief it is my great pleasure and honour to welcome ... Read More

Journal of Bioequivalence & Bioavailability Announces Special Issue Invitation

Image The Journal of Bioequivalence & Bioavailability (ISSN: 2572-3103) is scheduled to celebrate its 12th anniversary in the year 2020. The journal has successfully released several issues of peer-reviewed articles collated from wide geographic locations across the world since its inception in the year 2009, in addition to several sp... Read More